You have to pick:

Assume being a vampire includes burning to death in sunlight, necessity to drink blood (or your strength and will to live diminish), aversion to onions and the cross, somewhat enhanced strength and speed, immunity to any form of death other than silver bullets and a wooden stake through your heart, and being irresistible to women.

Depends.
Are we talking Sparkly Twilight Vampires, or Sexy Dracula Vampires?

pfft, obviously have hands at the end of my legs. Who wouldn't enjoy having legs like monkies!

Sexy Dracula Vampires. The Twilight ones aren't real vampires.

Makes me wonder why we lost them in the first place.

They're hard to walk on. Picking this option will mean that walking will be very tiring and potentiallty painful for anything other than short distances. Still one of the better options here, though. :)

You might be able to get special shoes to help with the issue. Worst case, you can use a wheelchair/scooter/segway.

You would lower the risk of injury if you balled up your hand-feet into fists. And you can always tape your ankle-wrists.